KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX5
All Species:
22.73
Human Site:
S557
Identified Species:
41.67
UniProt:
P17844
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17844
NP_004387.1
614
69148
S557
V
S
A
G
I
Q
T
S
F
R
T
G
N
P
T
Chimpanzee
Pan troglodytes
A5A6J2
614
69100
S557
V
S
A
G
I
Q
A
S
F
R
T
G
N
P
T
Rhesus Macaque
Macaca mulatta
XP_001092491
840
92407
A773
Y
G
A
G
T
Y
G
A
S
S
T
T
S
T
G
Dog
Lupus familis
XP_861744
616
69300
S559
V
S
A
G
I
Q
T
S
F
R
T
G
N
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q61656
614
69302
S557
V
S
A
G
I
Q
T
S
F
R
T
G
N
P
T
Rat
Rattus norvegicus
NP_001007614
615
69221
S557
V
S
A
G
I
Q
T
S
F
R
T
G
N
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510775
682
76115
S625
V
S
A
G
I
Q
T
S
F
R
T
G
N
P
T
Chicken
Gallus gallus
NP_990158
595
66718
A539
F
A
A
A
G
M
Q
A
G
F
R
A
G
N
P
Frog
Xenopus laevis
NP_001084230
608
68332
R552
S
N
V
Q
S
G
F
R
A
G
A
Q
N
G
T
Zebra Danio
Brachydanio rerio
NP_997777
518
59152
L462
A
H
D
L
V
S
V
L
R
E
A
H
Q
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C718
501
55558
Y445
A
G
A
K
G
T
A
Y
T
F
F
T
V
A
N
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
N485
I
M
R
E
A
N
Q
N
I
P
P
E
L
L
K
Red Bread Mold
Neurospora crassa
Q7SBC6
562
60181
Q506
V
L
Q
E
A
K
Q
Q
I
D
P
R
L
A
E
Conservation
Percent
Protein Identity:
100
99.6
52.3
99.6
N.A.
98.2
99.1
N.A.
88.5
88.1
81.7
71.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
58.5
99.6
N.A.
98.5
99.3
N.A.
89.4
92
88.7
78.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
20
100
N.A.
100
100
N.A.
100
6.6
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
33.3
100
N.A.
100
100
N.A.
100
20
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.5
51.1
52.4
Protein Similarity:
N.A.
N.A.
N.A.
61.4
64.1
65.4
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
70
8
16
0
16
16
8
0
16
8
0
24
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
16
0
0
0
0
0
8
0
8
0
0
8
% E
% Phe:
8
0
0
0
0
0
8
0
47
16
8
0
0
0
0
% F
% Gly:
0
16
0
54
16
8
8
0
8
8
0
47
8
8
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
8
0
0
0
47
0
0
0
16
0
0
0
0
0
8
% I
% Lys:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
8
0
8
0
0
0
8
0
0
0
0
16
8
0
% L
% Met:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
8
0
0
0
0
54
8
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
16
0
0
47
8
% P
% Gln:
0
0
8
8
0
47
24
8
0
0
0
8
8
0
0
% Q
% Arg:
0
0
8
0
0
0
0
8
8
47
8
8
0
0
0
% R
% Ser:
8
47
0
0
8
8
0
47
8
8
0
0
8
0
0
% S
% Thr:
0
0
0
0
8
8
39
0
8
0
54
16
0
8
54
% T
% Val:
54
0
8
0
8
0
8
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _